Imports System.Data.OleDb
Public Class Form1
    Dim connetionString As String
    Dim connection As OleDbConnection
    Dim oledbAdapter As OleDbDataAdapter
    Dim oledbCmdBuilder As OleDbCommandBuilder
    Dim ds As New DataSet
    Dim changes As DataSet
    Dim i As Integer
    Dim sql As String

    Private Sub Button1_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button1.Click
        connetionString = "Provider=Microsoft.Jet.OLEDB.4.0;Data Source=Your mdb filename;"
        connection = New OleDbConnection(connetionString)
        Sql = "select * from tblUsers"
        Try
            connection.Open()
            oledbAdapter = New OleDbDataAdapter(Sql, connection)
            oledbAdapter.Fill(ds)
            DataGridView1.Data Source= ds.Tables(0)
        Catch ex As Exception
            MsgBox(ex.ToString)
        End Try
    End Sub

    Private Sub Button2_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button2.Click
        Try
            oledbCmdBuilder = New OleDbCommandBuilder(oledbAdapter)
            changes = ds.GetChanges()
            If changes IsNot Nothing Then
                oledbAdapter.Update(ds.Tables(0))
            End If
            ds.AcceptChanges()
            MsgBox("Save changes")
        Catch ex As Exception
            MsgBox(ex.ToString)
        End Try
    End Sub
End Class