Imports System.Data.OleDb
Public Class Form1
    Private Sub Button1_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button1.Click
        Dim connetionString As String
        Dim connection As OleDbConnection
        Dim oledbAdapter As New OleDbDataAdapter
        Dim sql As String
        connetionString = "Provider=Microsoft.Jet.OLEDB.4.0;Data Source=Your mdb filename;"
        connection = New OleDbConnection(connetionString)
        sql = "delete from Users where UserID = 'user1'"
        Try
            connection.Open()
            oledbAdapter.DeleteCommand = connection.CreateCommand
            oledbAdapter.DeleteCommand.CommandText = sql
            oledbAdapter.DeleteCommand.ExecuteNonQuery()
            MsgBox("Row(s) Deleted !! ")
        Catch ex As Exception
            MsgBox(ex.ToString)
        End Try
    End Sub
End Class